Carnosine supplement review, 250 mg, 500 mg dosage, benefit as antioxidant, for cataract and Parkinson's disease, this nutrient has a number of health benefits that are just beginning to be explored. Carnosine (beta-alanyl-L-histidine) is a natural antioxidant found in the body and also available through foods and supplements. It can help reduce glycation.Properties
Camosine is a naturally occurring, water-soluble dipeptide. It has buffering activities in excitable animal and human tissues, exhibits metal ions binding properties, antioxidant and antiglycating properties, extends the life-span of cultured human diploid cells, regulates sarcoplasmic reticulum calcium-release channel activity. Carnosine may be a potential therapeutic agent (neurodegenerative, metabolic, cardiovascular diseases) mainly due to its antioxidant and antiglycating activities.
Health benefit
Carnosine is found exclusively in animal tissues, such as brain and skeletal muscle tissues. It is a potent hydrophilic antioxidant, antiglycating agent, reactive oxygen species scavenger and pH-buffer. Carnosine has potential benefits in many diseases of central nervous system, such as Alzheimer's disease, Parkinson's disease and cerebral ischemic diseases. Only a few human studies have been published regarding the health benefits. The early research looks quite promising.
Athletics and exercise
Using carnosine and natural antioxidants for the prophylaxis of acute post-loading oxidative stress.Eksp Klin Farmakol. 2007;. The effects of a submaximum single physical load with a mixed aerobic-anaerobic character (combined rowing test) on the intensity of lipid peroxidation (LPO) processes, antioxidant state of the organism, and rheological properties of blood have been studied in a group of athletes. The administration of natural antioxidants significantly decreased the LPO stress induced by the physical load, reduced the suppression of the antioxidant system of the organism, and normalized the LPO-disturbed hemorheological parameters. Antioxidants such as carnosine, cytamine, and apilac can be used as non-doping means for the accelerated recovery and increase in the physical work capacity in athletes.
Carnosine side effects, is it safe?
No major side effects have been reported in medical journals with this dipeptide supplement. One short term adverse effect is alertness and shallow sleep when very high dosages are supplemented.