Herpes simplex viruses (HSV)

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Genital herpes is caused by infection with herpes simplex virus (HSV). There are two types of HSV, HSV-1 and HSV-2, both of which belong to a wider group called Herpesviridae. Another well-known virus in this group is varicella zoster virus, which causes chicken-pox and shingles. In general:
HSV-1 is acquired orally, causing cold sores.
SV-2 is acquired during sexual contact and affects the genital area.
Although genital herpes used to almost always be caused by HSV-2 infection, HSV-1 is accounting for an increasing number of cases of genital herpes in developed countries. Only around 10-25 percent of people infected with HSV-2 are aware they have genital herpes. This is because genital herpes will often produce mild symptoms or no symptoms at all (asymptomatic infection). As a result, many cases of genital herpes go undiagnosed and frequently people unknowingly pass the virus on to their sexual partners.
If symptoms do occur, they will usually appear 2 to 7 days after exposure and last 2 to 4 weeks. Both men and women may have one or more symptoms, including:
  • Itching or tingling sensations in the genital or anal area;
  • small fluid-filled blisters that burst leaving small painful sores (seeSTD pictures);
  • pain when passing urine over the open sores (especially in women);
  • headaches;
  • backache;
  • flu-like symptoms, including swollen glands or fever.
Subsequent outbreaks are usually milder and last for a shorter period of time, usually 3 to 5 days. The sores are fewer, smaller, less painful and heal more quickly, and there are no flu-like symptoms. Subsequent outbreaks, or primary outbreaks in people who have had the virus for some time but have previously been asymptomatic, usually occur during periods of stress or illness when the immune system is functioning less efficiently than normal.
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Methemoglobinemia

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The diagnosis of methemoglobinemia should be considered in patients presenting with cyanosis and hypoxia. A variety of frequently used medications are capable of inducing methemoglobinemia, with dapsone and benzocaine being common culprits. Unique features, such as a saturation gap and chocolate-brown-colored blood, can raise suspicion for methemoglobinemia. Typically, symptoms correlate with the methemoglobin level, and treatment with methylene blue is reserved for patients with significantly elevated methemoglobin levels. In the presence of comorbid conditions that impair oxygen transport, however, low-grade methemoglobinemia can become symptomatic and may warrant treatment.
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Forskolin

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What is forskolin?

Forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) is the main active ingredient in the Ayurvedic herb Coleus forskohlii. Coleus is a member of the mint family and grows in subtropical areas in India, Burma, and Thialand. Forskolin has been extensively researched. It has also recently gained popularity as a fat loss agent.

What other benefits does forskolin have?
  • Cardiovascular health - Many studies have shown forskolin, as well as other actives in Coleus forskohlii, support cardiovascular health.

 Are there any side effects?

There are no major side effects reported in the literature, but you should consult a doctor before using forskolin if you are being treated for any conditions listed where drug interactions may occur. Large doses of forskolin will also probably make one drowsy, as it is an antihistamine. If this becomes a problem, one can reduce dosage, take it in combination with a stimulant, and/or take it before bed.

What are some good supplements to take along with forskolin?

Since there are still no strong clinical trials supporting the use of forskolin for weight loss yet, it is most commonly used as an adjunct to a weight loss regimen rather than a primary strategy. In studies, it is usually used along with a lipolytic hormone, so it may operate synergistically with a supplement that increases lipolytic hormone levels. Some of the best products containing forskolin in an adequate dosage are SAN Tight, or ISS Lipovar 8.
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Qnexa

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Qnexa Side Effects

Qnexa is an investigational prescription diet pill and weight maintenance drug. The obesity drug combines low doses of the appetite suppressant phentermine and the epilepsy drug topiramate, which increases a person's sense of being full. Phentermine is also sold under the brand name Adipex and topiramate is also sold asTopamax.The most common side effects of Qnexa in clinical trials were changes in taste, tingling, dryness in the mouth, respiratory infection, and constipation.Qnexa is manufactured by the biopharmaceutical company Vivus, Inc. Qnexa was rejected by the FDA on October 28, 2010 due to the risk of side effects such as depression, suicidal thoughts, pregnancy complications and memory lapses. Therefore, Qnexa is not currently available for use in the United States. However, the FDA is re-evaluating the drug based on new research, and is poised to deliver a decision in April of 2012. Qnexa may be not be indicated for women of childbearing age, as it can cause cleft palate birth defects.



Qnexa Side Effects

Results from the clinical trials addressed during the FDA's safety review of Qnexa returned several side effects of note. The FDA saw increases in heart rate among patients taking the drug, but the clinical significance was not conclusive. Other side effects included:
  • Increased anxiety
  • Sleep disturbances
  • Dry mouth
  • Tingling
  • Constipation
  • Altered taste
  • Depression
  • Infections in the sinus and respiratory tracts
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7 Keto

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How to Use It

Manufacturer of 7-KETO recommends 100 mg twice daily for weight loss with 7 Keto.

Where to Find It

7-KETO is available as a dietary supplement. Check out some of the best selling 7 Keto Supplements.

Possible Deficiencies

Since the level of 7-KETO is directly related to the level of DHEA in the body, people with lower DHEA levels likely have low 7-KETO levels as well. Low DHEA levels are primarily associated with aging.
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